The purpose of this website is to provide information about the Whooley Questions for depression screening.



  • A positive test (~95% sensitivity) identifies patients who may benefit from further evaluation.

  • A negative test essentially rules out depression.

  • The Whooley Questions (~65% specificity) cannot be used to diagnose or measure the severity of depression.



Mary A. Whooley, MD FACP FAHA FACC

Professor of Medicine, Epidemiology and Biostatistics

University of California, San Francisco

Director, Center for Healthcare Improvement and Medical Effectiveness

4150 Clement Street (111A1)

San Francisco, CA 94121