The purpose of this website is to provide information about the Whooley Questions for depression screening.



  • A positive test (~95% sensitivity) identifies patients who may benefit from further evaluation.
  • A negative test essentially rules out depression.
  • Reference: Whooley MA, Avins AL, Miranda J, Browner WS. Case-finding instruments for depression: two questions are as good as many. J Gen Int Med. 1997 Jul; 12(7):439-45. PubMed PDF




   Mary A. Whooley, MD FACP FAHA FACC
   Professor of Medicine, Epidemiology and Biostatistics
   University of California, San Francisco
   Director, Center for Healthcare Improvement and Medical Effectiveness
   4150 Clement Street (111A1) San Francisco, CA 94121